DRUGS WON’T WORK

^{I’ve seen a hardening of the arteries and senility become obsolete. I’ve seen the term dementia take a back seat to Alzheimer’s Disease (A.D.).}

^{It’s not unreasonable to conclude that a person having a significant buildup of oxidative stress (tissue inflammation), and drying or dried tissue due to a lack of water}

^{would have memory problems. Add long-term stress to that and you have someone that has serious memory problems, probably dementia. There’s a good chance that this person would be diagnosed as having Alzheimer’s Disease (A.D.).}

^{Time and millions, possibly billions of dollars have been spent by the pharmaceutical industry on drug research and trials trying to effect a cure for A.D. The best they’ve been able to come up with are a few drugs that slow the process. It’s time for a change in thinking.}

^{The earmarks of A.D. are a severely shrunken brain, fibroid tangles and clumps of Tau and Amyloid Beta protein.}

^{The pharmaceutical industry has approached A.D. as if there was something wrong with the person’s brain. They ‘ve been trying to find a drug that will cure the problem}

^{That’s not going to happen because there’s nothing wrong with the brain. When a person’s brain loses blood and water, to survive the brain will shrink itself to accommodate the amount of blood and water it’s receiving.}

^{It’s doing exactly what it needs to do to survive. Unfortunately, it costs us our memory and cognitive abilities.}

^{When I say the brain is doing what it’s supposed to do, I’m excluding actual diseases of the brain like Frontal Lobe dementia, Lewes body dementia, and dementia caused by sickle cell anemia.}

^{What we have to accept is that the brain is a living, self-managing organ focused on survival.}

^{Your blood should carry, everything your brain needs to survive. Your blood should carry the water your brain needs. But that blood with its water content is only made available to the brain. You have to have working cells that draw the blood and hydrate the tissue. Hydrated tissue provides a bed for the cells and allows them to function. Drying tissue reduces cell function and memory. Your brain will shrink itself to accommodate the amount of blood and water it’s receiving. Dry tissue prevents function and memory causing your brain to shrink itself even further, eliminating cell function and seriously reducing memory.}

^{Your blood and what it carries are critical to the health and functioning of your brain.} 

^{To prevent Alzheimer’s we need to do those things that get blood to the brain with the oxygen, water, glucose, protein, antioxidants, and Omega-3 fatty acid that’s needed.}

^{Go back to the three-legged stool. The first leg, the leg responsible for memory, isn’t going to be strong unless the second and third legs are strong. If all three legs are strong the seat will be sturdy. If the seat is sturdy your memory and cognitive abilities will be good. It’s up to the individual and what they’re doing that determines the strength of the stool and their memory. A weak stool will result in a shrinking brain and a weak memory. If you have a weak memory, you have weak cognition. A broken stool will result in some form of dementia, probably A.D.}

^{If you accept the fact that your brain is a living, self-managing organ focused on survival, you will understand why you can prevent A.D. by doing those things needed to keep the three legs of the stool strong. If you keep the three legs of the stool strong, the seat will be sturdy, your brain won’t shrink, and your memory and cognitive abilities will be good.}

^{If the legs of the stool are weak and wobbly they’ll get smaller to retain their strength and the seat will shrink to accommodate the strength of the legs. The weaker the legs get the smaller the seat. The smaller the seat the poorer your memory. As your memory gets worse so do your cognitive abilities}

^{I’ve taken care of the shrinking brain with good science. For the fibroid tangles and the clumps of Tau and Amyloid beta protein I’m going to rely on the laws of physics.}

^{There’s a law in physics that says that matter can’t disappear. It can change form like water does to steam, but it can’t just disappear. If the brain is shrinking, there’s a lot of dry tissue that’s missing. In my simplified version of the markers of A.D., the shrunken tissue becomes the fibroid tangles. There has to be a correlation between the amount of brain tissue that’s shrunk and the mass of fibroid tangles.  That takes us to the clumps of Tau and Beta Amyloid protein.}

^{Experience-dependent brain cells are primarily protein. The role that Tau and Amyloid Beta protein play in cell biology is not clear. However, it is clear that Tau and Amyloid Beta protein play a role in cell biology. The clumps of protein are the residual of the dried cells.}

^{The earmarks of Alzheimer’s are the earmarks of a brain that’s dying because of a lack of blood and water. Medicine isn’t going to fix that. Only the individual with Alzheimer’s can affect the amount of blood and water going to their brain.}

^{The next question is “Can A.D. be reversed?”  My studies and experience tell me that the answer to that question depends on three things; The degree to which the brain has shrunk, the amount of time that can be devoted to rehab, and a spouse or partner willing to be supportive.}

^{When working with someone having A.D. you have to recognize that the person is embarrassed,  frightened, and most likely angry. They’re embarrassed because you’re dealing with the seat of their intelligence. They’re frightened because they don’t know what’s going to happen to them next, and they’re angry because it’s happening to them and they don’t know why.}    

^{Taking medicine is an easy answer, but it doesn’t do anything more than slow things down for a while and put money into the pockets of pharmaceutical companies.}

^{The only way that A.D. is going to be prevented is by maintaining the three-legged stool.}